با همکاری مشترک دانشگاه پیام نور و انجمن روانشناسی اجتماعی ایران

نوع مقاله : علمی- پژوهشی

نویسندگان

1 گروه روانشناسی، دانشکده علوم تربیتی و روانشناسی، دانشگاه شهید مدنی آذربایجان، تبریز، ایران

2 گروه روانشناسی، دانشکده روانشناسی و علوم تربیتی، دانشگاه شهید مدنی آذربایجان، تبریز، ایران

10.30473/hpj.2026.76615.6366

چکیده

مقدمه: ترس از عود بیماری، یکی از شایع‌ترین مشکلات روان‌شناختی در نجات‌یافتگان از سرطان است که کیفیت زندگی آنان را تحت تأثیر قرار می‌دهد. پژوهش حاضر با هدف مدل‌یابی معادلات ساختاری ترس از عود بیماری بر اساس خودشفقت‌ورزی و ذهن‌آگاهی با نقش میانجی‌گر تاب‌آوری در بیماران مبتلا به سرطان انجام شد.
روش: روش این پژوهش توصیفی-همبستگی مبتنی بر مدل‌یابی معادلات ساختاری است. جامعه آماری شامل کلیه بیماران سرطانی عضو انجمن پژواک شهر تبریز در سال 1402-1403 بود که از میان آن‌ها 150 نفر به روش نمونه‌گیری هدفمند انتخاب شدند. ابزار گردآوری داده‌های پژوهش شامل فرم کوتاه پرسشنامه‌های ترس از عود (FCRI-SF) سیمارد و ساوارد (2009)، پرسشنامه شفقت به خود (SCS-SF) رائس و همکاران (2011)، پرسشنامه ذهن‌آگاهی فرایبورگ (FMI-SF) والاچ و همکاران (2006) و پرسشنامه تاب‌آوری کانور و دیویدسون (CD-RISC-10) کمپبل-سیلس و استاین  (۲۰۰۷) بود. تحلیل داده‌ها با نرم‌افزارهای SPSS24 و SmartPLS3 انجام شد.
یافته‌ها: نتایج مدل معادلات ساختاری نشان داد که خودشفقت‌ورزی (47/0-)، ذهن‌آگاهی (48/0-) و تاب‌آوری (49/0-) با ترس از عود رابطه منفی و معناداری دارند (01/0p<). مدل‌یابی معادلات ساختاری نیز آشکار کرد که خودشفقت‌ورزی (26/0-) و ذهن‌آگاهی (60/0-) به‌طور مستقیم، و همچنین به‌طور غیرمستقیم از طریق میانجی‌گری تاب‌آوری، تأثیر منفی و معناداری بر ترس از عود بیماری دارند. مدل از برازش مطلوبی برخوردار بود.
نتیجه‌گیری: یافته‌ها نقش میانجی تاب‌آوری را به‌عنوان سازوکاری مهم در رابطه خودشفقت‌ورزی و ذهن‌آگاهی با ترس از عود برجسته می‌سازد. تقویت این مؤلفه‌ها می‌تواند در طراحی مداخلات روان‌شناختی برای کاهش ترس از عود در بیماران سرطانی مؤثر باشد.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

Structural Equation Modeling of Fear of Disease Recurrence based on Self-Compassion and Mindfulness with the Mediating Role of Resilience in Cancer Patients

نویسندگان [English]

  • Leila Taghizadeh niagh 1
  • Ezzatollah Ahmadi 2
  • Karim Abdolmohamadi 1

1 Department of Psychology, Faculty of Education and Psychology, Azarbaijan Shahid Madani University, Tabriz,, Iran

2 Faculty of Education and Psychology, Azarbijan Shahid Madani University, Tabriz, Iran

چکیده [English]

Objective: Cancer is recognized as a fundamental global health challenge, profoundly affecting patients' quality of life. Among the numerous psychological complications stemming from the lived experience of cancer, "fear of cancer recurrence" (FCR) is reported as one of the most prevalent and distressing symptoms, with approximately 62% of cancer survivors experiencing high levels of this anxiety. This persistent fear of disease return not only hinders the patient's reintegration into normal daily life but also lays the groundwork for deep cognitive vulnerabilities and psychological distress. According to the Self-Regulatory Executive Function (S-REF) model, the activation of the cognitive-attentional syndrome (including rumination and threat monitoring) fuels the persistence of these chronic worries. In this framework, strengthening protective psychological resources can play a crucial role in mitigating these symptoms. Self-compassion (facing suffering with kindness and non-judgment) and mindfulness (purposeful, non-judgmental attention to the present moment) are two key components of self-regulation that enhance an individual's cognitive coping capacity when facing illness. Furthermore, resilience, defined as the ability to restore psychological equilibrium, plays a critical adaptive and buffering role in this path. Despite numerous studies, no structural model has yet been designed to simultaneously evaluate self-compassion and mindfulness, mediated by resilience, on the fear of recurrence in cancer patients. Therefore, the present study aimed to conduct structural equation modeling of the fear of disease recurrence based on self-compassion and mindfulness, with the mediating role of resilience, in patients with cancer. Method: The present study employed a descriptive-correlational design using Structural Equation Modeling (SEM). The statistical population comprised all cancer patients who were members of the Pezhvak Cancer Support Charity Association in Tabriz during the years 2023–2024. Using the Cochran (Plout) formula, the minimum required sample size for the model was estimated at 66 participants; however, to increase statistical power and ensure the reliability of the modeling results, 150 patients were selected via purposive sampling. Data collection instruments consisted of four standard questionnaires with established psychometric properties: 1) the Fear of Cancer Recurrence Inventory–Short Form (FCRI-SF) with 12 items; 2) the Self-Compassion Scale–Short Form (SCS-SF) with 12 items; 3) the Freiburg Mindfulness Inventory–Short Form (FMI-SF) with 14 items; and 4) the Connor-Davidson Resilience Scale (CD-RISC-10) with 10 items. Following coordination with the association and obtaining written informed consent from the patients, the questionnaires were completed by the participants. Ethical principles, including data confidentiality and the right to voluntary withdrawal, were strictly observed. Descriptive and demographic data were analyzed using SPSS (version 24). Evaluation of the conceptual model fit and analysis of the structural relationships (direct and indirect paths) were conducted through the partial least squares (PLS) approach utilizing SmartPLS (version 3) software. Results: Descriptive findings revealed that the majority of participants were aged between 36 and 50 years (62.6%), and most were female (64.6%) and married (57.3%). The descriptive indicators of the variables, including means and standard deviations, are reported in Table 1. Pearson correlation matrix results indicated that self-compassion (r=-0.47), mindfulness (r=-0.48), and resilience (r=-0.49) had significant negative relationships with fear of disease recurrence (p<0.01). Evaluation of the measurement model fit indices (Cronbach’s alpha, rho, composite reliability, and AVE) showed acceptable values well above the standard threshold. Furthermore, the structural model demonstrated a good fit (SRMR=0.065, NFI=0.910). Path analysis findings revealed that self-compassion exerted a significant direct negative effect on fear of recurrence (β=-0.26, t=5.17, p<0.01). Similarly, mindfulness showed a significant direct negative effect on FCR (β=-0.60, t=17.47, p<0.01). In addition, mediation hypotheses were supported; self-compassion had an indirect negative effect on FCR through the mediating role of resilience (β=-0.20, t=3.45, p<0.01), and mindfulness similarly exerted an indirect negative effect on FCR via resilience (β=-0.15, t=4.87, p<0.01). Thus, resilience plays a significant mediating role in these structural pathways.Conclusion: This study aimed to explain the fear of disease recurrence in cancer patients based on self-compassion and mindfulness, with the mediating role of resilience. Structural equation modeling results demonstrated that self-compassion and mindfulness exert significant direct and indirect negative effects (mediated by resilience) on reducing FCR, aligning with prior research. In explaining the effect of self-compassion, this construct replaces self-criticism with a kind and accepting attitude, bolstering patients' cognitive capacity to cope with challenges and preventing them from becoming trapped in a vicious cycle of anxiety. Mindfulness, by training non-judgmental present-moment awareness, helps patients view thoughts of disease return merely as transient mental events rather than reflections of reality, thereby reducing pain catastrophizing. Furthermore, enhancing these two components strengthens resilience as a dynamic coping resource. Resilient patients exhibit greater psychological flexibility in the face of stressors and suffer less from cognitive-attentional distress, which subsequently mitigates FCR. Ultimately, this study was limited by its reliance on self-report instruments and a sample restricted to Tabriz. Nonetheless, the findings confirm that resilience, self-compassion, and mindfulness are crucial psychological pillars in reducing patient distress. Fortifying these components in clinical protocols and psychological interventions in hospitals and cancer counseling centers will be highly effective.

کلیدواژه‌ها [English]

  • Cancer
  • Fear of Disease Recurrence
  • Mindfulness
  • Resilience
  • Self-Compassion
Abedini, M., Akbari, B., Sadeghi, A., & Asadimajreh, S. (2021). The relationship between resilience and mindfulness with emotional well-being with the mediating role of emotion regulation in cancer. Health Psychology, 10(39), 67–84. (In Persian) https://doi.org/10.30473/hpj.2021.58344.5172
Ağaç, M., & Üzar-Özçetin, Y. S. (2022). Psychological resilience, metacognitions, and fear of recurrence among cancer survivors and family caregivers. Cancer Nursing, 45(2), 454–462. https://doi.org/10.1097/NCC.0000000000000973
Ahmadi, S. A., Vaziri, S., Ahi, G., Lotfi-Kashani, F., & Akbari, M. E. (2021). Comparison of acceptance and commitment therapy and spiritual therapy in reducing fear of relapse among patients with breast cancer. Salāmat-i Ijtimāī (Community Health), 8(3), 413–426. (In Persian) https://doi.org/10.22037/ch.v8i3.31223
Badakhshan, M., Sarafraz, M. R., & Imani, M. (2023). The effectiveness of self-compassion intervention on impulsivity among students who have experienced romantic breakup. Journal of Psychology, 26(4), 376–385. (In Persian) http://www.iranapsy.ir/Article/36748/FullText
Baer, R. A. (Ed.). (2006). Mindfulness-based treatment approaches: Clinician's guide to evidence base and applications. Academic Press. https://doi.org/10.1016/B978-0-12-088519-0.X5000-X
Bateni, F., & Alikhani, R. (2019). Control of Psychological Symptoms and Pain in Critically Ill Patients with Cancer: Psychological components and cognitive-behavioral interventions. Journal of Iranian Society of Anesthesiology and Intensive Care, 41(2), 41-45. (In Persian) https://journals.sbmu.ac.ir/isacc/index.php/iranesthesia/article/view/315
Bishop, S. R., Lau, M., Shapiro, S., Carlson, L., Anderson, N. D., Carmody, J., Segal, Z. V., Abbey, S., Speca, M., Velting, D., & Devins, G. (2004). Mindfulness: A proposed operational definition. Clinical Psychology: Science and Practice, 11(3), 230–241. https://doi.org/10.1093/clipsy.bph077
Braun, T. D., Park, C. L., & Gorin, A. (2016). Self-compassion, body image, and disordered eating: A review of the literature. Body Image, 17, 117–131. https://doi.org/10.1016/j.bodyim.2016.03.003
Bray, F., Laversanne, M., Sung, H., Ferlay, J., Siegel, R. L., Soerjomataram, I., & Jemal, A. (2024). Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 74(3), 229–263. https://doi.org/10.3322/caac.21834
Brown, J. S., Amend, S. R., Austin, R. H., Gatenby, R. A., Hammarlund, E. U., & Pienta, K. J. (2023). Updating the definition of cancer. Molecular Cancer Research, 21(11), 1142–1147. https://doi.org/10.1158/1541-7786.MCR-23-0411
Butler, E. A., Egloff, B., Wilhelm, F. H., Smith, N. C., Erickson, E. A., & Gross, J. J. (2003). The social consequences of expressive suppression. Emotion, 3(1), 48–67. https://doi.org/10.1037/1528-3542.3.1.48
Campbell-Sills, L., & Stein, M. B. (2007). Psychometric analysis and refinement of the Connor-Davidson Resilience Scale (CD-RISC): Validation of a 10-item measure of resilience. Journal of Traumatic Stress, 20(6), 1019-1028. https://doi.org/10.1002/jts.20271
Cancer Research Center of Iran. (2024). Moarefi-e rais-e markaz [Introducing the head of the center]. Retrieved August 7, 2025, (In Persian) https://crc.sbmu.ac.ir/%D9%85%D8%B9%D8%B1%D9%81%DB%8C-%D8%B1%D8%A6%DB%8C%D8%B3-%D9%85%D8%B1%DA%A9%D8%B2
Connor, K. M., & Davidson, J. R. T. (2003). Development of a new resilience scale: The Connor-Davidson Resilience Scale (CD-RISC). Depression and Anxiety, 18(2), 76–82. https://doi.org/10.1002/da.10113
Delkhosh, A., & Movahedi, Y. (2023). The effectiveness of mindfulness training on the resilience and ambiguity tolerance of breast cancer patients. Iranian Journal of Rehabilitation Research in Nursing, 9(2), 22–31. (In Persian) https://sid.ir/paper/1126824/en
Esmaili, S., Nikoogoftar, M., Yaghoobi, S., & Nazari, R. (2024). The mediating role of coping strategies and resilience in the relationship between stressful life events and positive and negative emotions in women with breast cancer. Quarterly Journal of Health Psychology, 13(51), 21–36. (In Persian) https://doi.org/10.30473/hpj.2024.68222.5834
Faghani, F., Choobforoushzadeh, A., Sharbafchi, M. R., & Poursheikhali, H. (2022). Effectiveness of mindfulness-based supportive psychotherapy on posttraumatic growth, resilience, and self-compassion in cancer patients: A pilot study. Wiener klinische Wochenschrift, 134(15-16), 628–636. https://doi.org/10.1007/s00508-021-01962-9
Fann, J. R., Thomas-Rich, A. M., Katon, W. J., Cowley, D., Penning, M., McGregor, B. A., & Gralow, J. (2008). Major depression after breast cancer: A review of epidemiology and treatment. General Hospital Psychiatry, 30(2), 112–126. https://doi.org/10.1016/j.genhosppsych.2007.10.008
Ghasemi Jobaneh, R., Arab Zadeh, M., Jalili Nikoo, S., Mohammad Alipoor, Z., & Mohsenzadeh, F. (2015). Survey the Validity and Reliability of the Persian Version of Short Form of Freiburg Mindfulness Inventory. Journal of Rafsanjan University of Medical Sciences, 14(2), 137–150. (In Persian) http://journal.rums.ac.ir/article-1-2293-fa.html
Kabat-Zinn, J. (1990). Full catastrophe living: Using the wisdom of your mind and body to face stress, pain, and illness. Delacorte Press.
Kavehfarsani, Z., Salehi, R., & Rabiee, M. (2020). Investigating the role of self-compassion and psychological capital (hope, resilience, self-efficacy and optimism) in predicting depression and death anxiety in patients with cancer. Rooyesh-e-Ravanshenasi Journal, 9(10), 103–114. (In Persian) http://frooyesh.ir/article-1-2067-fa.html
Kemper, K. J., Mo, X., & Khayat, R. (2015). Are mindfulness and self-compassion associated with sleep and resilience in health professionals? The Journal of Alternative and Complementary Medicine, 21(8), 496–503. https://doi.org/10. 1089/acm.2014.0281
Khanjani, S., Foroughi, A. A., Sadghi, K., & Bahrainian, S. A. (2016). Psychometric properties of Iranian version of self-compassion scale (short form). Pajoohande, 21(5), 282-289. (In Persian) http://pajoohande.sbmu.ac.ir/article-1-2292-fa.html
Krok, D., Telka, E., & Skalski-Bednarz, S. B. (2025). Be kind to yourself: Testing self-compassion, fear of recurrence, and generalized anxiety in women with cancer within a multiple-mediation model. Journal of Clinical Medicine, 14(13), Article 4696. https://doi.org/10.3390/ jcm14134696
Lebel, S., Ozakinci, G., Humphris, G., Mutsaers, B., Thewes, B., Prins, J., & Butow, P. (2016). From normal response to clinical problem: Definition and clinical features of fear of cancer recurrence. Supportive Care in Cancer, 24(8), 3265–3268. https://doi.org/10.1007/s00520-016-3272-5
Li, Y., Mao, C., Zhu, S., Gao, L., Li, P., & Gao, W. (2019). The effect of resilience on fear of cancer recurrence in breast cancer patients: the moderating role of perceived social support. Chinese Journal of Practical Nursing, 35(24), 1846-1853. https://rs.yiigle.com/ CN11 5399202004/1162017.htm
Maheu, C., Singh, M., Tock, W. L., Eyrenci, A., Galica, J., Hébert, M., Frati, F., & Estapé, T. (2021). Fear of cancer recurrence, health anxiety, worry, and uncertainty: A scoping review about their conceptualization and measurement with breast cancer survivorship research. Frontiers in Psychology, 12, 644932. https://doi.org/10. 3389/fpsyg.2021.644932
Mehrzad, Y., Bagheri, N., & Mojtabaie, M. (2025). Structural equation modeling of the psychological distress based on self-compassion with the mediating role of negative body image in married women with breast cancer. Quarterly Journal of Health Psychology, 14(55), 99–116. (In Persian) https://doi.org/10.30473/hpj. 2025 .73174.6158
Mirahmadi, Z., Khezri Moghadam, N., & Rahmati, A. (2022). Predicting pain catastrophizing based on psychological resilience and mindfulness in patients with cancer: Mediating role of positive emotions. Shenakht Journal of Psychology and Psychiatry, 9(5), 130–141. (In Persian) https :// sid.ir/paper/1077759/en
Miravaisi, S., Ahmadian, H., Ghaderi, B., & Moradi, O. (2023). Structural model of pain acceptance based on mindfulness and the difficulty of emotional regulation with the mediating role of resilience in cancer patients. Scientific Journal of Kurdistan University of Medical Sciences, 28(5), 95–107. (In Persian) http://sjku.muk.ac.ir/article-1-6534-fa.html
Muris, P., & Petrocchi, N. (2017). Protection or vulnerability? A meta-analysis of the relations between the positive and negative components of self-compassion and psychopathology. Clinical Psychology & Psychotherapy, 24(2), 373–383. https://doi.org/10.1002/cpp.1965
Naseri Garagoun, S., Mousavi, S. M., Shabahang, R., & Bagheri Sheykhangafshe, F. (2021). The effectiveness of mindfulness-based stress reduction intervention on resilience and life expectancy of gastrointestinal cancers patients. Iranian Journal of Psychiatric Nursing, 9(2), 60–71. (In Persian) http://ijpn.ir/article-1-1759-fa.html
Neff, K. D. (2003a). Self-compassion: An alternative conceptualization of a healthy attitude toward oneself. Self and Identity, 2(2), 85–102. https://doi.org/10.1080 /15298860309032
Neff, K. D. (2003b). The development and validation of a scale to measure self-compassion. Self and Identity, 2(3), 223–250. https://doi.org/10.1080/15298860309027
Nematpour Darzi, A. A., Basharpoor, S., & Moslemi, D. (2024). The effectiveness of mindfulness-based cancer recovery training on pain catastrophizing and perceived stress of cancer patients. Health Psychology, 13(51), 67-82. (In Persian) https://doi.org/10.30473 /hpj.2024.70011.5985
Ng, D. W. L., Foo, C. C., Ng, S. S. M., Kwong, A., Suen, D., Chan, M., Or, A., Chun, O. K., Fielding, B. F. S., & Lam, W. W. T. (2020). The role of metacognition and its indirect effect through cognitive attentional syndrome on fear of cancer recurrence trajectories: A longitudinal study. Psycho-Oncology, 29(2), 271–279. https://doi.org/10.1002/pon.5234
Özonder Ünal, I., & Ordu, C. (2023). Alexithymia, self-compassion, emotional resilience, and cognitive emotion regulation: Charting the emotional journey of cancer patients. Current Oncology, 30(10), 8872–8887. https://doi.org/10 .3390/curroncol30100641
Raes, F. (2010). Rumination and worry as mediators of the relationship between self-compassion and depression and anxiety. Personality and Individual Differences, 48(6), 757–761. https://doi.org/10.1016/j.paid.2010.01.023
Raes, F., Pommier, E., Neff, K. D., & Van Gucht, D. (2011). Construction and factorial validation of a short form of the Self-Compassion Scale. Clinical Psychology & Psychotherapy, 18(3), 250–255. https://doi.org/10.1002/cpp.702
Reed, E., Wheeler, D., & Scanlon, K. (2012). Spotlight on secondary breast cancer: A policy initiative to influence the care of women with metastatic breast cancer. Breast Cancer Management, 1(3), 201–207. https://doi. org/10.2217/bmt.12.18
Rezaeipandari, H., Mohammadpoorasl, A., Morowatisharifabad, M. A., & Shaghaghi, A. (2022). Psychometric properties of the Persian version of abridged Connor-Davidson Resilience Scale 10 (CD-RISC-10) among older adults. BMC Psychiatry, 22(1), 493. https://doi .org/10.1186/s12888-022-04138-0
Sabariego, C., Brach, M., Herschbach, P., Berg, P., & Stucki, G. (2011). Cost-effectiveness of cognitive-behavioral group therapy for dysfunctional fear of progression in cancer patients. The European Journal of Health Economics, 12(5), 489–497. https://doi.org/10 .1007/s10198-010-0266-y
Segal, Z., Dimidjian, S., Vanderkruik, R., & Levy, J. (2019). A maturing mindfulness-based cognitive therapy reflects on two critical issues. Current Opinion in Psychology, 28, 218–222. https://doi.org/10.1016/j.copsyc.2019.01.015
Simard, S., & Savard, J. (2009). Fear of Cancer Recurrence Inventory: development and initial validation of a multidimensional measure of fear of cancer recurrence. Supportive Care in Cancer, 17(3), 241-251. https://doi.org/10.1007/s00520-008-0444-y
Tamannaeifar, M. R., Mansourinik, A., & Golestani, E. (2023). The relationship between body image and adjustment in breast cancer patients: The mediating role of self-compassion and psychological resilience. J Feyz Med Sci, 27(3), 288-297. (In Persian) http://feyz.kaums .ac.ir/article-1-4855-fa.html
Thewes, B., Kaal, S. E., Custers, J. A., Manten-Horst, E., Jansen, R., Servaes, P., & Husson, O. (2018). Prevalence and correlates of high fear of cancer recurrence in late adolescents and young adults consulting a specialist adolescent and young adult (AYA) cancer service. Supportive Care in Cancer, 26(5), 1479–1487. https://doi.org/10.1007/s00520-017-3974-3
Walach, H., Buchheld, N., Buttenmüller, V., Kleinknecht, N., & Schmidt, S. (2006). Measuring mindfulness—the Freiburg Mindfulness Inventory (FMI). Personality and Individual Differences, 40(8), 1543-1555. https://doi.org/10.1016/j.paid.2005.11.025
Wang, X., Dai, Z., Zhu, X., Li, Y., Ma, L., Cui, X., & Zhan, T. (2024). Effects of mindfulness-based stress reduction on quality of life of breast cancer patient: A systematic review and meta-analysis. PLoS ONE, 19(7), e0306643. https:// doi.org/10.1371/journal.pone.0306643
Wells, A., & Matthews, G. (1996). Modelling cognition in emotional disorder: The S-REF model. Behaviour Research and Therapy, 34(11–12), 881–888. https://doi. org/10.1016 /S0005-7967(96)00050-2
Zhu, L., Yao, J., Wang, J., Wu, L., Gao, Y., & Xie, J. (2019). The predictive role of self-compassion in cancer patients' symptoms of depression, anxiety, and fatigue: A longitudinal study. Psycho-Oncology, 28(9), 1918–1925. https://doi.org/10.1002/pon.5174.