Payame Noor University Health Psychology 2322-1283 10 37 2021 05 22 Comparing the Efficacy of Cognitive–Behavioral Therapy and Processingemotion Regulation on Anxiety Sensitivity of Patients with Multiple Sclerosis Comparing the Efficacy of Cognitive–Behavioral Therapy and Processingemotion Regulation on Anxiety Sensitivity of Patients with Multiple Sclerosis 109 126 7771 10.30473/hpj.2021.54697.4917 FA Nafiseh Mohammad Department of Psychology, Kish International Branch, Islamic Azad University, Kish Island, Iran. Mohammad Hatami Associate Professor, Department of Psychology, Kharazmi University, Tehran, Iran. Mojgan Niknam Assistant Professor, Department of Psychology, Roodehen Branch, Islamic Azad University, Tehran, Iran. Journal Article 2020 08 18 <strong>Objective: </strong>The aim of this study was to compare the efficacy cognitive-behavioral therapy,processing emotion regulation and mixed intervention on anxiety sensitivity of patients with multiple sclerosis. <strong>Method:</strong> The present study was a quasi-experimental study with pretest-posttest design and follow-up. The population of the research includes all M.S. patients with registered medical records in M.S. Association of Tehran in2020. 30 patients were selected by available and random sampling in three experimental groups. Training groups were treated for 3 months based on cognitive behavioral therapy, emotion regulation and mixed intervention. Anxietysensitivity  were measured by Reiss and Peterson anxietysensitivity questionnaire before, after, and 3 months after the intervention. <strong>Findings:</strong> The results showed that there was a significant difference (p≤0.05) between the effectiveness of the three treatments on patients' anxiety sensitivity. The results of the Tukey test showed that group with mixed intervention compared to the other interventions and processing emotion regulation respect to cognitive-behavioral therapy had lower mean in both post-test and follow-up stages. <strong>Conclusion:</strong> The results of this study showed the effect of cognitive behavioral therapy, processing emotion regulation and mixed intervention on decrease of anxiety sensitivity  in patients with Multiple sclerosis. <strong>Objective: </strong>The aim of this study was to compare the efficacy cognitive-behavioral therapy,processing emotion regulation and mixed intervention on anxiety sensitivity of patients with multiple sclerosis. <strong>Method:</strong> The present study was a quasi-experimental study with pretest-posttest design and follow-up. The population of the research includes all M.S. patients with registered medical records in M.S. Association of Tehran in2020. 30 patients were selected by available and random sampling in three experimental groups. Training groups were treated for 3 months based on cognitive behavioral therapy, emotion regulation and mixed intervention. Anxietysensitivity  were measured by Reiss and Peterson anxietysensitivity questionnaire before, after, and 3 months after the intervention. <strong>Findings:</strong> The results showed that there was a significant difference (p≤0.05) between the effectiveness of the three treatments on patients' anxiety sensitivity. The results of the Tukey test showed that group with mixed intervention compared to the other interventions and processing emotion regulation respect to cognitive-behavioral therapy had lower mean in both post-test and follow-up stages. <strong>Conclusion:</strong> The results of this study showed the effect of cognitive behavioral therapy, processing emotion regulation and mixed intervention on decrease of anxiety sensitivity  in patients with Multiple sclerosis. https://hpj.journals.pnu.ac.ir/article_7771_d4da4bb7ca525e47a7c64a4609890981.pdf