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arezoo moradi tavalaei; Imanollah Bigdeli; Ali Mashhadi; Mahdi Razmara; mohammad Jafferany
Abstract
Objective: Alopecia areata (AA) is a complex autoimmune condition with non-scarring alopecia, and it occurs in approximately 2% of the global population. Although its pathogenesis includes both genetic and immunological factors, mounting evidence supports the significance of psychological determinants ...
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Objective: Alopecia areata (AA) is a complex autoimmune condition with non-scarring alopecia, and it occurs in approximately 2% of the global population. Although its pathogenesis includes both genetic and immunological factors, mounting evidence supports the significance of psychological determinants in inducing as well as exacerbating the condition. The transdiagnostic approach, which is a method characterizing key psychological processes underlying greater than one disorder, offers a new paradigm to study AA's psychosocial determinants. The current research analyzes how transdiagnostic factors, particularly neuroticism, anxiety sensitivity, emotion regulation, mindfulness, and experiential avoidance, correlate with severity of AA and emotional comorbidities in an Iranian clinical sample. Our research contributes to closing relevant gaps in extant research in that: (1) the variables are compared simultaneously, not separately, and (2) a full mediation model is considered to shed light on personality-outcome pathways. Method: We performed a cross-sectional survey of 200 AA patients (123 men, 77 women; mean age=29.93±7.93 years) enrolled from clinics of dermatology of Imam Reza Hospital, Mashhad. Candidates were confirmed by board-certified dermatologists for AA diagnosis, while disease severity was measured using the Alopecia Areata Severity Index (AASI). All participants completed validated Persian versions of Multidimensional Emotional Disorder Inventory (MEDI) for emotional disorders, Anxiety Sensitivity Index-16 (ASI-16), Freiburg Mindfulness Inventory-Short Form (FMI-SF), Gross & John Emotion Regulation Questionnaire (ERQ), Multidimensional Experiential Avoidance Questionnaire (MEAQ). Structural Equation Modeling (SEM) through Smart-PLS 3.0 examined direct/indirect associations between transdiagnostic variables, with mediation testing through bootstrapping (5000 samples). The research was ethically approved in ethical commite of ferdowsi university of Mashhad (IR.UM.REC.1402.174). Results: Key findings of this study are: Neuroticism had the highest correlation with emotional disorders (β=0.819, p<0.001), explaining 67.1% variance. High neuroticism predicted lower mindfulness (β=-0.560) and higher disease severity (β=0.206). Mindfulness mediated 38.7% of neuroticism's effect on emotional disorders (β=-0.206, p<0.001) and reduced experiential avoidance (β=-0.687). Anxiety sensitivity had direct effects on emotional disorders (β=0.280) and emotion dysregulation (β=-0.393), but indirect effects through avoidance were nonsignificant (p=0.818). Counter hypotheses, emotion dysregulation, and experiential avoidance could not mediate psychological effects (p>0.05). The demographic variable of age/sex showed few effects of moderation (all p>0.10). Conclusion: This study provides the first evidence for transdiagnostic mechanisms in AA, identifying neuroticism and mindfulness as pivotal treatment targets. We suggest for: Revised AA management guidelines incorporating psychological assessments, Development of brief mindfulness interventions tailored for dermatology settings, Increased collaboration between dermatologists and psychologists. These innovations could transform AA from a purely dermatological condition to a biopsychosocial model of care, potentially improving treatment adherence and reducing relapse rates.
Javad Ayoubi; Imanollah Bigdeli; Ali Mashhadi
Abstract
Objective: The purpose of this study was to investigate the effectiveness of mindfulness-integrated cognitive behavior therapy on quality of life, psychological distress and adherence to therapy in patients with type II diabetes mellitus. Method: The method of research was quasi-experimental with pretest-posttest ...
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Objective: The purpose of this study was to investigate the effectiveness of mindfulness-integrated cognitive behavior therapy on quality of life, psychological distress and adherence to therapy in patients with type II diabetes mellitus. Method: The method of research was quasi-experimental with pretest-posttest control group. The sample included 30 persons who were selected by purposeful sampeling among people with type II diabetes mellitus that were divided randomly into two group (experimental and control, N=15). After that an 8 session of MiCBT was done for the experimental group but The control group did not received any intervention. Measures included: world health organization quality of life (WHOQOL), depression, anxiety and stress scale (DASS-21) and Modanloo adherence to therapy test. Findings: result of univariate covariance analysis was statistically significant on quality of life (p<0/05, F=151/65), psychological distress (p<0/05, F=69/178) and adherence (p<0/05, F=36/146). Conclusion: It is suggested that mindfulness-integrated cognitive behavior therapy decreased psychological distress symptoms and improved quality of life and adherence to therapy in patients with type II diabetes mellitus.
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Mohammad Javad Rabbani Parsa; Ali Mashhadi; Imanollah Bigdeli
Volume 7, Issue 26 , September 2018, , Pages 44-61
Abstract
Objective: The aim of this study was to investigate the effectiveness of motivational interviewing in reducing emotional eating and anxiety considering the moderator role of impulsivity in obese people. Method: This is a quasi-experimental study with pretest-posttest and control group. 20 obese patients, ...
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Objective: The aim of this study was to investigate the effectiveness of motivational interviewing in reducing emotional eating and anxiety considering the moderator role of impulsivity in obese people. Method: This is a quasi-experimental study with pretest-posttest and control group. 20 obese patients, who had referred to Jooyandegane Salamat, Dr. Sobhani and Rosha diet therapy clinics at Mashhad, selected voluntarily regarding inclusion criteria. Results: ANCOVA results showed that levels of emotional eating (F(1,15)=5/89, P≤ 0/05) and anxiety (F(1,17)=6/87, P≤0/05) have significantly reduced in examination group. Also, it was found that impulsivity has not a moderator role in the effect of motivational intervention on emotional eating. Conclusion: the Motivational interviewing is an effective method to reduce emotional eating and anxiety in obese people and so is a way to help them control their weight
